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Updated: Jun 19, 2025

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显著的顺序死亡复合体调节热和IL-1β释放,以应对Yersinia阻断免疫信号的反应

Ronit Schwartz Wertman1, Winslow Yost1, Beatrice I Herrmann1

  • 1Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.

Science advances
|July 26, 2024
PubMed
概括

叶菌感染触发了一种独特的细胞死亡途径,涉及酶-8和酶-1,与典型的炎症酶激活不同. 这项研究揭示了在病原体诱导的免疫信号屏蔽期间,热和IL-1β释放的新型机制.

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