在儿童中罕见的放射性表现的染色体病变:柱状模式:一个回顾性队列研究研究
Ahmet Salduz1, Serkan Bayram1, Mesut Bulakci2
1Department of Orthopaedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Medicine
|July 26, 2024
概括
柱状软骨的图案,是一种罕见的发现,在染色体病,出现在垂直的软骨柱子在physis. 这种模式往往代表正常的骨发育,通常不需要手术.
科学领域:
- 骨辐射学 骨辐射学
- 儿科整形外科 儿科整形外科
- 发展生物学 发展生物学
背景情况:
- 柱状软骨图案是一种罕见的放射性发现,其特点是身体附近的平行软骨柱.
- 它通常与染色体炎有关,但对于临床医生来说通常并不熟悉.
研究的目的:
- 为了阐明体内柱状软骨模式的临床和放射学特征.
- 为了更好地了解其与染色体病的关联,并指导管理.
主要方法:
- 追溯评估15名患有柱状图案和色肌病的患者.
- 分析临床数据,X射线,CT和MRI发现.
- 将其分类为带着柱状图案的有限性染色体 (LE-CP) 和多重性染色体.
主要成果:
- 柱状图案病变在X射线/CT上显示为低密度的垂直/斜管状区域.
- 核磁共振显示信号特征类似于形软骨板.
- 大多数柱状软骨经历了正常的内分泌骨化.
- 对于最多3个受影响身体的患者,LE-CP被定义为LE-CP.
结论:
- 柱状的图案是一个罕见的表现,常常反映正常的内分泌骨化.
- 它可能代表体的发育异常,而不是瘤.
- 外科手术通常不适合,除非骨折或严重的变形是一个风险.
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