与术后认知功能障碍相关的结果:系统性审查和元分析.
Patumporn Suraarunsumrit1,2,3, Varalak Srinonprasert1,2,3, Tanawan Kongmalai1,3,4
1Mahidol University Health Technology Assessment (MUHTA) Graduate Program, Mahidol University, Bangkok, Thailand.
Age and ageing
|July 26, 2024
概括
手术后的术后认知功能障碍 (POCD) 增加了死亡风险和住院时间,特别是在30天内. 早期识别这些神经认知变化对于干预和改善患者结果至关重要.
科学领域:
- 医学研究 医学研究
- 神经科学是一个神经科学.
- 外科手术的结果
背景情况:
- 手术后认知功能障碍 (POCD) 是手术后认知能力的下降.
- POCD可能会导致不良结果.
- 波多野结衣症对身体功能,住院,痴呆和死亡率的影响需要进一步调查.
研究的目的:
- 探索POCD对身体功能,住院时间 (LOS),痴呆和死亡率的影响.
- 通过手术类型 (心脏与非心脏) 和评估时间 (<30天与>=30天) 来分层分析POCD影响.
主要方法:
- 在PubMed和Scopus的系统文献搜索到2023年5月.
- 包括评估POCD的研究和主要手术患者的相关结果.
- 按手术类型和评估时间对POCD影响的分层.
主要成果:
- 在心脏手术 (RR 2.04) 和非心脏手术 (RR 1.84) 后,POCD与功能衰退无关,但死亡风险增加.
- 在30天内患有POCD的患者经历了更长的住院时间 (心脏病的MD为1.37天,非心脏病的MD为1.94天).
- 手术后妄 (POD) 可能导致异质性;报告的数据有限.
结论:
- 在心脏或非心脏手术后30天内发生的POCD与较差的结果和增加的死亡风险有关.
- 早期识别术后神经认知障碍对于及时干预至关重要.
- 需要进一步的研究来区分POD与POCD对临床结果的影响.
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