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Updated: Jun 19, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET

Published on: August 17, 2022

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振动能量景观和GPCR中的能量流

Humanath Poudel1, David J Wales2, David M Leitner1

  • 1Department of Chemistry, University of Nevada, Reno, Nevada 89557, United States.

The journal of physical chemistry. B
|July 26, 2024
PubMed
概括

这项研究引入了断开连接图来可视化蛋白质能量景观,揭示了诸如林和甘氨酸等特定氨基酸如何影响G蛋白结合受体 (GPCR) 中的能量流. 活跃和不活跃状态的差异突出显示了全性调节机制.

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