在慢性阿片类药物使用者中,持续的家庭阿片类药物剂量减少了腹修复后的阿片类药物的总使用量
Caitlin Crosier1, Katherine Hoffman1, Kevin Walker1
1Prisma Health Department of Surgery, USA.
American journal of surgery
|July 26, 2024
概括
在住院治疗腹修复 (VHR) 期间继续患者的家庭阿片类药物剂量减少了术后阿片类药物处方,而没有增加补充量. 这种方法有助于在外科环境中慢性阿片类药物管理.
科学领域:
- 外科手术 手术手术
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在慢性阿片类药物治疗的患者中,治疗术后疼痛存在重大挑战.
- 对于这些患者的最佳术后管理策略,数据有限.
- 这项研究解决了在进行手术的慢性阿片类药物使用者的管理中需要基于证据的协议的需求.
研究的目的:
- 评估假设,持续在慢性阿片类药物治疗中接受腹修复 (VHR) 的患者的家庭阿片类药物剂量会降低术后阿片类药物消费.
- 在这个患者群体中建立一个术后阿片类药物管理协议.
主要方法:
- 在2017年6月至2022年3月期间,对658名接受VHR治疗的患者进行了回顾性审查.
- 117名患者被确定为慢性阿片类药物使用者.
- 43名患者在持续家庭阿片类药物剂量协议下进行管理,而74名患者没有.
主要成果:
- 住院患者每天的吗啡毫克相当量 (MME) 消费在协议和非协议组之间是相似的 (34对36 MME).
- 按照协议管理的患者在出院时获得的MME处方明显较低 (80对225 MME;p < 0.001).
- 补充率在两组之间是可比的 (21.4%对25.4%).
结论:
- 对于接受VHR的慢性阿片类药物使用者来说,持续的家庭阿片类药物治疗方案导致在出院时减少阿片类药物处方.
- 这种管理策略不会导致对处方补充的需求增加.
- 这些发现支持采用该方案,以改善慢性阿片类药物使用者的术后疼痛管理.
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