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Updated: May 5, 2026

Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy
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Preparation of Tumor Antigen-loaded Mature Dendritic Cells for Immunotherapy

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通过过度激活树突细胞,在老老鼠中"增强"瘤免疫力

Jiaqi Liu1, Feng Shao2

  • 1Graduate Program in Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China; National Institute of Biological Sciences, Beijing, P.R. China.

Cell
|July 26, 2024
PubMed
概括

年龄增长会影响瘤免疫治疗. 研究人员发现过度激活的树突细胞通过NLRP3炎症体促进T细胞反应, 消除老鼠的瘤, 提供新的治疗途径.

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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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