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Updated: Jun 19, 2025

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
14:32

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates

Published on: February 27, 2016

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对防御相关的Sirtuin蛋白的自抑制和激活的结构性见解

Xu Yang1, Yiqun Wang1, Jianting Zheng2

  • 1State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

International journal of biological macromolecules
|July 26, 2024
PubMed
概括

细菌防御相关的Sirtuin 2 (DSR2) 蛋白是不活跃的,直到菌体蛋白结合. 新的结构揭示了DSR2如何激活以降解NAD+,增强细菌对菌体的防御机制.

关键词:
这就是DSR2的DSR2.纳达酶活动的NADase活动.在SIR2中,SIR2是SIR2.

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