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Updated: Jun 19, 2025

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PGRMC1通过破坏TRIM56介导的AHR的无处不在,促进NSCLC的干细胞表型

Anqi Guan1, Ziyu Dai2, Chen Jiang2

  • 1Department of Geriatrics, Xiangya Hospital, Central South University, Changsha 410008, China; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha 410008, China.

Biochimica et biophysica acta. Molecular basis of disease
|July 26, 2024
PubMed
概括

孕激素受体膜组件1 (PGRMC1) 通过抑制AHR无处不在,驱动癌症干细胞 (CSC) 特性和非小细胞肺癌 (NSCLC) 的化学抵抗. 这揭示了NSCLC的一个新的治疗点.

关键词:
美国人权委员会 (AHR)在NSCLCLC中,我们可以看到.在PGRMC1中使用.一个的子.在 TRIM56 里面,你会看到 TRIM56.无处不在的关系

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