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在复杂的内血管大动脉动脉瘤修复后,术后结果的性别相关差异
Claudia Trogolo-Franco1, Shernaz S Dossabhoy1, Sabina M Sorondo1
1Division of Vascular and Endovascular Surgery, Department of Surgery, Stanford, CA.
Annals of vascular surgery
|July 26, 2024
概括
复杂的内血管大动脉动脉瘤修复 (EVAR) 结果在两性之间是相似的,尽管女性具有更具挑战性的解剖学. 在复杂的EVAR后,女性表现出更好的长期功能维护.
科学领域:
- 血管外科 血管外科
- 血管内修复 血管内修复
- 大动脉动脉瘤治疗方法
背景情况:
- 由于解剖学变异,女性性别与复杂的EVAR中较差的结果有关.
- 这项研究调查了复杂的EVAR结果中的基于性别的差异.
研究的目的:
- 为了比较女性和男性患者之间复杂EVAR的30天外科和长期结果.
- 在复杂的EVAR中识别潜在的性别特异性挑战和好处.
主要方法:
- 对293个复杂的EVAR案件 (2012-2023) 的回顾性审查.
- 对30天复合终点 (主要不良事件,透析,死亡) 和技术结果的分析.
- 评估长期结果,包括功能,死亡率和重新干预.
主要成果:
- 女性呈现出较小的动脉瘤,更多的胸腔腹部参与,以及增加动脉化.
- 尽管30天的综合结果相似,但女性的辅助导管使用率更高,住院时间更长.
- 长期随访显示,女性的功能下降率明显较低.
结论:
- 复杂的EVAR在具有具有挑战性的解剖学的女性中是可行的,实现与男性相比的30天和长期结果.
- 女性在复杂EVAR后的长期功能下降方面表现出保护作用.
- 进一步的研究是有必要的,以了解改善女性结局背后的机制.
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