在患有小大动脉年的患者中进行过导管大动脉置换:基于性别的结果的倾向匹配分析
Danial Ahmad1, Michel Pompeu Sá1, Amber Makani2
1Department of Cardiothoracic Surgery; UPMC Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
The American journal of cardiology
|July 26, 2024
概括
在患有小主动脉环 (SAA) 的患者中,透气管主动脉置换 (TAVR) 的结果在男性和女性中是相似的. 这项研究发现,在SAA中TAVR后,死亡率或中风再入院率没有显著的基于性别的差异.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 小动脉环形 (SAA) 在接受过导管动脉置换 (TAVR) 的女性中更为常见.
- 了解SAA患者的性别特异性结果对于TAVR手术成功至关重要.
研究的目的:
- 为了比较以性别为基础的和倾向匹配的结果,指数跨导管大动脉置换 (TAVR) 在小大动脉环 (SAAs) 的患者.
主要方法:
- 从2012年到2023年对3,911名TAVR患者进行了回顾性机构分析.
- 按性别分层,重点关注661名SAA患者 (环径小于23毫米).
- 1:1倾向匹配创建了152对对结果在30天和1年进行比较.
主要成果:
- 男人手术后心脏起器植入率较高 (8.6%与3.3%相比),女性有 iliofemoral 解剖 (4.6%与0%相比).
- 假肢患者不匹配率在两性之间没有显著差异.
- 30天死亡率为0%,一年死亡率为4.3%,没有显著的性别差异. 手术前肌素的增加预测了更高的死亡风险,而不是性别.
结论:
- 在患有小主动脉环 (SAA) 的患者中,透气管大动脉置换 (TAVR) 的结果在两性之间是可比的.
- 在SAA中TAVR的安全性和有效性在男性和女性中都很明显.
- 性别不是SAA人群中TAVR结果的重要预测因素.
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