Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Auditory Pathway01:15

Auditory Pathway

5.4K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
5.4K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

4.3K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.3K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

931
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
931
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

1.5K
The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...
1.5K
What is a Sensory System?01:31

What is a Sensory System?

93.1K
Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
93.1K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

3.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Mammalian Brains Seen through the Lens of Evolution.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

The role of transthalamic pathways in perception.

Communications biology·2026
Same author

A Reconsideration of Parallel Processing in Vision: Importance of Lower Spatial Frequencies to Form Vision.

The European journal of neuroscience·2025
Same author

DISRUPTION OF TRANSTHALAMIC CIRCUITRY FROM PRIMARY VISUAL CORTEX IMPAIRS VISUAL DISCRIMINATION IN MICE.

bioRxiv : the preprint server for biology·2025
Same author

Synaptic integration of somatosensory and motor cortical inputs onto spiny projection neurons of mice caudoputamen.

The European journal of neuroscience·2024
Same author

Transthalamic Pathways for Cortical Function.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2024

相关实验视频

Updated: Jun 19, 2025

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging
06:05

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging

Published on: September 18, 2015

8.3K

一个对感知至关重要的 transthalamic 途径.

Christina Mo1,2, Claire McKinnon3, S Murray Sherman4

  • 1The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, Australia. christina.mo@florey.edu.au.

Nature communications
|July 26, 2024
PubMed
概括

感官处理至关重要的 Transthalamic 路径,传递与任务相关的信息以进行感知. 抑制这些途径损害了小鼠的纹理歧视,揭示了它们在决策中的低估作用.

更多相关视频

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
10:59

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

15.3K
In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices
09:07

In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices

Published on: September 20, 2019

11.4K

相关实验视频

Last Updated: Jun 19, 2025

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging
06:05

Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging

Published on: September 18, 2015

8.3K
Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
10:59

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury

Published on: November 19, 2012

15.3K
In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices
09:07

In Vivo Intracerebral Stereotaxic Injections for Optogenetic Stimulation of Long-Range Inputs in Mouse Brain Slices

Published on: September 20, 2019

11.4K

科学领域:

  • 神经科学是一个神经科学.
  • 感官处理 感官处理
  • 感知决策 - - 感知决策

背景情况:

  • 感知依赖于皮层处理和区域间通信.
  • 跨体内 (皮质-体内-皮质) 路径与直接的皮质皮质路径平行,但研究不足.
  • 在感官处理中 transthalamic 路径的作用仍然在很大程度上未被探索.

研究的目的:

  • 为了研究 transthalamic 途径在感官处理和感知决策中的作用.
  • 为了确定 transthalamic 路径是否传播与任务相关的信息来进行感官决策.
  • 通过检查 transthalamic 途径的功能来挑战皮质中心的感知观点.

主要方法:

  • 在小鼠的更高阶体感性丘脑中,对 transthalamic 路径的光遗传抑制.
  • 小鼠执行了基于纹理的歧视任务.
  • 双光子成像监测了主要和次要体感皮质中的细胞活动.

主要成果:

  • 抑制跨甲状腺通路严重损害了纹理分辨性能.
  • 直接的皮质皮质突出仍然完好无损,这表明 transthalamic 路线的关键作用.
  • 细胞对纹理刺激的反应不受影响,但纹理选择性受到干扰,特别是在二级皮层.
  • 这种选择性中断在二级皮质中更加明显,表明了前影响.

结论:

  • 跨thalamic通路对于将任务相关信息传播到用于感知决策的更高阶皮质至关重要.
  • 这些路径是被低估的等级路线,对感官知觉至关重要.
  • 这些发现挑战了纯粹的皮质中心感知模型,突出了跨体内沟通的重要性.