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Updated: Jun 19, 2025

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环极和抗癌药物诺斯卡之间的结合机制:光谱和分子对接研究

Arezu Hosseiny1, Zahra Talebpour2,3, Zahra Garkani-Nejad4

  • 1Department of Analytical Chemistry, Faculty of Chemistry, Alzahra University, Vanak, Tehran, Iran.

Journal of fluorescence
|July 26, 2024
PubMed
概括

这项研究探讨了抗癌药物诺斯卡 (NOS) 如何与β环极素 (β-CD和M-β-CD) 结合,以改善其特性. 甲基β-β 环极 (M-β-CD) 复合物表现出更高的稳定性和结合效率.

关键词:
贝内西 - 希尔德布兰德方程贝塔-环德克斯林是一种β-环德克斯林包容性复杂的包容性复杂的甲基β-β-循环德克斯特林.分子对接是分子对接.负偏差 在船尾-Volmer.

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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