KIAA1429通过YTHDF1-介导的m6A修饰来增加FOXM1表达,以促进多发性骨髓瘤中的有氧糖解和瘤发生

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Yue Wu1, Yi Luo2, Xingchen Yao1

  • 1Department of Orthopedics, Beijing Chao-Yang Hospital, No.8 Gongti South Rd, Chaoyang District, Beijing, 100020, China.

Cell biology and toxicology
|July 26, 2024
PubMed
概括

高KIAA1429水平通过通过YTHDF1-FOXM1通路促进有氧糖解和细胞增殖,驱动多发性骨髓瘤 (MM) 的进展. 准KIAA1429抑制了MM的生长,提供了一个潜在的治疗策略.

关键词:
有氧糖溶解是有氧的.在FOXM1中,我们可以看到FOXM1.在KIAA142929中使用.多发性骨髓瘤是一种多发性骨髓瘤.在 YTHDF1 的位置上.m6A 一个很好的.

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