早期干预希尔施普朗格病:对肠球炎和手术结果的影响
Yunhan Zhang1, Xiao Xiang1, Xunfeng Li1
1Department of neonatal surgery, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Children's Hospital of Chongqing Medical University, Chongqing, China.
BMC pediatrics
|July 26, 2024
概括
在Hirschsprung的早期手术.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床结果研究研究
背景情况:
- 希尔施普朗格病 (HSCR) 管理涉及有争议的手术时间.
- 评估手术年龄对中期结果的影响至关重要.
研究的目的:
- 评估HSCR患者手术时的年龄与中期结果之间的相关性.
- 根据手术时间来比较门功能和生活质量.
主要方法:
- 对235名HSCR患者 (2015-2019) 的回顾性分析.
- 分为两组的分层:手术<3个月与3-12个月.
- 并发症,门功能 (Rintala尺度) 和生活质量的比较 (PedsQLTM4.0).
主要成果:
- 两组之间在术后肠功能或生活质量方面没有显著差异.
- 在<3个月组中,与希尔施普朗相关的肠球炎 (HAEC) 的发生率显著降低 (69.1%与30.9%相比).
结论:
- 手术年龄在HSCR中没有显著影响中期门功能或生活质量.
- 早期干预 (<3个月) 可以减少HAEC的发生率,最大限度地减少肠切除,缩短手术时间.
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