肝细胞癌与主要血管侵袭的治疗方法
Tomoko Tadokoro1, Joji Tani1, Asahiro Morishita1
1Department of Gastroenterology and Neurology, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki, Kita, Takamatsu 761-0793, Kagawa, Japan.
Cancers
|July 27, 2024
概括
肝细胞癌的血管侵袭意味着预后不佳,通常需要联合治疗. 治疗策略旨在管理门高血压并降低手术后高复发率.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 在瘤学瘤学.
- 血管外科 血管外科
背景情况:
- 肝细胞癌 (HCC) 的血管侵袭呈现为主要血管中的瘤塞,表明预后不佳.
- 这种情况经常与门高血压有关,需要仔细评估和管理.
- 目前的治疗方案包括手术,化疗和放射治疗,但复发率仍然很高.
研究的目的:
- 为肝细胞癌与血管入侵的治疗策略提供全面的概述.
- 突出与管理HCC血管侵袭相关的挑战,包括高复发率和单一疗法的有效性有限.
- 强调需要采用多模式治疗方法的需要.
主要方法:
- 这是一个叙事综述,综合了当前关于HCC血管侵袭治疗的知识.
- 关于治疗干预的文献搜索,包括手术切除,药物治疗和放射治疗.
- 对治疗结果和复发模式的分析.
主要成果:
- 血管侵袭是HCC的关键预后因素.
- 肝切除虽然是主要治疗,但与高复发率有关.
- 系统疗法通常有效性有限,特别是在肝功能受损的患者中.
- 组合疗法,包括辅助药物和新辅助药物疗法,通常是必要的.
结论:
- 多模式治疗方法对于管理血管侵袭的HCC至关重要.
- 在肝切除术前后结合治疗可能会改善结果.
- 需要进一步的研究来优化治疗策略,提高这些患者的生存率.
相关概念视频
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Stem Cell Therapy for Tissue Regeneration
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Tumor Immunotherapy
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Esophageal Varices-II: Clinical Features and Management
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Venous Thrombosis III: Interprofessional Care
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...


