高风险皮肤黑色素瘤的临床和成像随访:当前证据和指导方针
John T Vetto1,2
1Department of Surgery, Division of Surgical Oncology, Oregon Health & Science University, Portland, OR 97239, USA.
Cancers
|July 27, 2024
概括
高风险黑色素瘤患者从监视成像中受益,正子发射断层扫描 (PET) 或计算机断层扫描 (CT) 是可行的选择. 大脑磁共振成像 (MRI) 是首选用于检测大脑转移.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 皮肤病学 皮肤病学
背景情况:
- 美国癌症联合委员会 (AJCC) 的分期系统将侵袭性皮肤黑色素瘤分为低风险 (阶段IA-IIA) 和高风险 (阶段IIB-IV) 组.
- 高风险黑色素瘤患者的监测成像缺乏统一的建议,原因是数据有限,多样化,尽管其直观的好处.
研究的目的:
- 审查目前的证据和对高风险黑色素瘤患者监测成像的建议.
- 突出成像在有效的全身疗法 (ESTs) 背景下的作用.
主要方法:
- 对黑色素瘤监测成像的回顾性和前性数据的审查.
- 分析当前的指导方针和专家对后续战略的意见.
- 考虑PET,CT和MRI等成像方式.
主要成果:
- 大多数数据支持在高风险黑色素瘤的随访中使用成像.
- 定子发射断层扫描 (PET) 或全身计算机断层扫描 (CT) 被认为是合理的后续选择.
- 在可行的情况下,建议使用脑磁共振成像 (MRI) 检测大脑转移.
结论:
- 成像在监测对有效全身疗法 (EST) 的反应和检测高风险黑色素瘤复发方面发挥着至关重要的作用.
- 需要对成像协议进行标准化,但目前的证据支持在高风险病例中使用它.
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