口腔腔 - - 另一个抗菌素耐药性黄金葡萄球菌的储存库?
Marek Chmielewski1, Oliwia Załachowska1, Dominika Komandera1
1Oral Microbiology Student Scientific Club, Medical Faculty, Medical University of Gdansk, 80-204 Gdansk, Poland.
Antibiotics (Basel, Switzerland)
|July 27, 2024
概括
口腔和鼻子一样有可能携带金黄色葡萄球菌,并且可以容纳抗生素耐药菌株. 这凸显了在医疗保健机构中查口腔携带的重要性.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 口腔健康 口腔健康
背景情况:
- 黄金葡萄球菌 (Staphylococcus aureus) 是一种常见的病原体,无症状地殖民于健康个体.
- 非鼻腔携带,特别是口腔携带,以及其在传播抗菌素耐药菌株中的作用尚不清楚.
- 临床前牙科学生是研究载体的相关人群,因为他们可能暴露于各种微生物环境中.
研究的目的:
- 确定在临床前牙科学生的口腔和鼻腔中黄金葡萄球菌的流行率.
- 评估这些部位的Staphylococcus aureus分离物的抗微生物敏感性概况.
- 为了研究口腔作为抗菌素耐药性黄金葡萄球菌的储存库的潜力.
主要方法:
- 收集了132名临床前牙科学生的264个口腔和鼻.
- 使用标准诊断程序培养标本.
- 根据EUCAST指南进行的抗菌敏感性测试.
主要成果:
- 黄金葡萄球菌在鼻腔 (11.4%) 和口腔 (9.1%) 中的比较流行率.
- 同时口腔和鼻腔运输的高率 (27.3%).
- 口腔和鼻腔分离物中抗生素耐药率相似,但口腔分离物中多药耐药性更高 (34%vs21.1%).
- 在两个地点检测到三例甲素耐药黄金葡萄球菌 (MRSA).
结论:
- 临床前牙科学生表现出类似的口腔和鼻腔黄金葡萄球菌携带率.
- 口腔可以作为抗微生物耐药菌株的殖民点,独立于鼻腔运输.
- 口腔是医疗机构中黄金葡萄球菌查的一个被忽视的部位.
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