评估患有急性冠状动脉综合征,接受皮肤冠状动脉干预的患者的认知功能:一项前性试点研究
Gozde Baran1, Suleyman Sezai Yildiz2, Ozge Gonul Oner3
1Department of Neurology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Research and Training Hospital, 34785 Istanbul, Turkey.
Diagnostics (Basel, Switzerland)
|July 27, 2024
概括
患有急性冠状动脉综合征 (ACS) 的年轻患者经历了暂时的认知障碍. 然而,急性冠状动脉综合征不会导致持久的结构性大脑变化,正如MRI扫描显示的那样.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 神经成像是一种神经成像.
背景情况:
- 患有急性冠状动脉综合征 (ACS) 的年轻患者的认知功能仍未得到充分研究.
- 评估潜在的大脑变化对于了解ACS在这个人口群体中的长期影响至关重要.
研究的目的:
- 调查认知功能和检测ACS接受皮肤冠状动脉干预 (PCI) 的年轻患者的大脑变化.
- 为了确定ACS是否与认知障碍和结构性大脑变化有关.
主要方法:
- 对50名年轻ACS患者进行前性研究,这些患者接受了初级PCI治疗.
- 大脑MRI评估白色和灰色物质的变化.
- 使用七个标准化测试进行认知功能评估,将基线与一个月的随访进行比较.
主要成果:
- 在第一天的25名患者中观察到过渡性认知障碍,18名患者在一个月后仍然表现出障碍.
- 认知障碍患者和没有认知障碍患者之间没有发现结构性大脑差异.
- 在Fazekas+组PCI后一天到一个月之间,Stroop测试表现和其他认知测试的显著差异被注意到.
结论:
- 患有ACS的年轻患者表现出暂时的认知功能障碍.
- 急性冠状动脉综合征与永久性结构性大脑变化无关.
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