在胃肠道癌症的挥发性有机化合物分析中采样和处理样本
Weiyang Zheng1, Yiyang Min2, Ke Pang2
1Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Diagnostics (Basel, Switzerland)
|July 27, 2024
概括
挥发性有机化合物 (VOC) 显示出对非侵入性癌症查的前景. 本综述涵盖了用于胃肠道癌症的VOC采样方法,强调了自动化和未来临床使用的改进.
科学领域:
- 生物化学 生物化学
- 分析化学 分析化学
- 在瘤学瘤学.
背景情况:
- 挥发性有机化合物 (VOC) 越来越多地被认为是其在非侵入性疾病检测方面的潜力.
- 胃肠道癌症需要改进查方法,因为对有效,负担得起和非侵入性选择的重大未满足需求.
研究的目的:
- 审查目前用于胃肠道癌症的VOC分析的采样方法.
- 讨论自动化VOC采样技术的进展.
- 建议改善样本采集和处理,以促进VOC分析的临床采用.
主要方法:
- 对VOC和胃肠道癌症诊断研究的文献综述.
- 详细讨论各种样本采集和制备技术.
- 对自动采样技术的最新发展进行分析.
主要成果:
- 样本准备对VOC分析的质量和可行性产生重大影响.
- 自动抽样技术代表了该领域的关键进展.
- 样品处理的标准化和优化对于临床应用至关重要.
结论:
- 挥发性有机化合物分析对非侵入性胃肠道癌症查具有显著的前景.
- 采样方法的进步,特别是自动化,对于临床翻译至关重要.
- 需要进一步改进样本采集和处理,以便在医疗保健机构普及VOC分析.
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