探索短期旅行对肠道微生物群和益生菌中介稳定性的影响
Yiming Zhao1, Chunyan Li1, Kaijuan Wu2
1Human Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha 410013, China.
Biomedicines
|July 27, 2024
概括
短期旅行会改变肠道微生物群,即使没有腹,也会增加波动. 旅行前的肠道微生物组成,特别是有益细菌,预测了这些变化和与旅行有关的肠道问题.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 旅行 医学 旅行 医学
背景情况:
- 旅行往往与胃肠道不适和腹有关.
- 众所周知,肠道微生物在与旅行有关的肠道问题中起着重要作用.
- 旅行期间肠道微生物群的动态尚不清楚.
研究的目的:
- 为了研究短期旅行对肠道微生物群组成的影响.
- 为了确定影响旅行期间肠道微生物群波动的因素.
- 探索旅行前肠道微生物群的潜力,作为旅行相关肠道健康的预测因素.
主要方法:
- 在为期一周的旅行之前和之后,从12名健康个体收集了便样本.
- 不旅行的控制被包括在内进行比较.
- 在72个便样本上进行了Amplicon测序和生物信息分析.
主要成果:
- 短期旅行显著增加了个体内肠道微生物群的波动,不管腹症状如何.
- 旅行前的初始肠道微生物群组成是这些波动的关键因素.
- 在旅行前,具有稳定的微生物群的旅行者表现出特定益生菌的丰富 (例如, *Agathobaculum*, *Faecalibacterium*, *Bifidobacterium*, *Roseburia*, *Lactobacillus*).
结论:
- 旅行前肠道微生物群的组成可以预测旅行期间的波动和潜在疾病.
- 特定的益生菌细菌可能在旅行期间在维持肠道健康方面发挥保护作用.
- 这项研究提供了一个以微生物为中心的观点,以了解和潜在地干预与旅行相关的肠道健康.
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