儿童牛皮的营养状况:在第三级护理推中心的病例对照研究
Adelina-Maria Sendrea1,2,3, Sinziana Cristea4, Carmen Maria Salavastru1,2
1Pediatric Dermatology Department, Carol Davila University of Medicine and Pharmacy, 8 Eroilor Sanitari Boulevard, 050474 Bucharest, Romania.
Children (Basel, Switzerland)
|July 27, 2024
概括
儿科牛皮与超重和肥胖的更高风险有关. 体重指数 (BMI) 升高与儿童指甲牛皮严重程度 (NAPSI) 的增加相关,强调需要控制体重.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 牛皮和肥胖是慢性炎症疾病,具有共同的病理生理因素.
- 牛皮越来越多地被认为是一种全身性炎症性疾病,具有外皮表现.
研究的目的:
- 为了研究身体质量指数 (BMI) 和儿科牛皮之间的关联.
- 评估儿童的BMI和牛皮严重程度 (PASI,NAPSI,DLQI) 之间的相关性.
主要方法:
- 一个病例控制研究,涉及100例儿科牛皮病例和100个年龄和性别匹配的对照.
- 用年龄和性别的BMI百分位来评估营养状况.
- 牛皮的严重程度使用牛皮区域和严重性指数 (PASI),指甲牛皮严重性指数 (NAPSI) 和皮肤病生活质量指数 (DLQI) 进行评估.
主要成果:
- 在儿童牛皮患者中,超重 (OR 6.93) 和肥胖 (OR 12.6) 的风险显著增加.
- 增加的BMI与更高的指甲牛皮严重程度指数 (NAPSI) 评分相关 (p = 0.000015).
- 在BMI和牛皮面积和严重性指数 (PASI) (p = 0.074) 或疾病持续时间之间没有发现显著的关联.
结论:
- 增加的BMI与牛皮的诊断和儿童牛皮指甲疾病严重程度的增加有关.
- 强调需要提高儿童牛皮患者超重/肥胖的认识和查.
- 建议进行进一步的大规模研究,以证实这些发现,并为管理策略提供信息.
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