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在中对与 SARS-CoV-2 主蛋白酶相互作用的 Ivermectin 和 Nirmatrelvir 抑制剂进行比较分析

Yuri Alves de Oliveira Só1, Katyanna Sales Bezerra2, Ricardo Gargano1

  • 1Institute of Physics, University of Brasília, Brasília 70910-900, Brazil.

Biomolecules
|July 27, 2024
PubMed
概括

尼尔马特雷尔维尔和伊弗梅克丁表现出与SARS-CoV-2主要蛋白酶 (Mpro) 具有明显的结合模式. 这两种药物都稳定了Mpro酶,为抗击COVID-19提供了潜在的治疗策略,而Ivermectin表明了持续的相互作用.

关键词:
我从来没有做过任何事情.尼尔马特里尔维尔 (Nirmatrelvir) 是一种这就是SARS-CoV-2病毒.主要蛋白酶 (Mpro) 的使用.分子对接的分子对接.分子动力学分子动力学

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