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在非典型的RPE65视网膜变症中,基因疗法后近视斑块孔和脱落:一个病例报告

Fabrizio Giansanti1,2, Cristina Nicolosi1,2, Dario Giorgio2,3

  • 1Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, 50134 Florence, Italy.

Genes
|July 27, 2024
PubMed
概括

在患有RPE65视网膜缩和高近视症的患者中,Voretigene Neparvovec (VN) 的视网膜下注导致斑点并发症. 迅速的手术干预成功地关闭了黄斑孔,并保持了视力敏度.

关键词:
在 RPE65 的情况下,它是 RPE65 的.并发症可能导致并发症.基因治疗的基因疗法黄斑孔是一个巨大的洞.视网膜炎的颜色化沃雷特基因和非沃维克的存在

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...