反氧酶P4HB和PDIA3与STIM1相互作用,以微调其敏感性和激活

Yangchun Du1, Feifan Wang1, Panpan Liu1

  • 1Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing 100875, China.

概括

蛋白质二硫化异构酶P4HB和PDIA3微调STIM1结合亲和力,调节存储运行的进入 (SOCE),对细胞信号和疾病至关重要. 这一发现揭示了STIM1的发展.

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