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Updated: Jun 19, 2025

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid
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A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

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在老鼠关节冠状细胞中透敏感的TREK通道:表达和功能作用

Arturo Ponce1, Alejandro Ogazon Del Toro1, Lidia Jimenez1

  • 1Department of Physiology, Biophysics and Neurosciences, Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV-IPN), Ciudad de México 07360, Mexico.

International journal of molecular sciences
|July 27, 2024
PubMed
概括

这项研究揭示了TREK-1和TREK-2通道存在于大鼠关节性淋巴细胞中. 这些发现表明,TREK通道可能通过机械感应在维持软骨完整性方面发挥作用.

关键词:
关节软骨 - 关节软骨机器敏感的道.透敏感通道的透敏感通道骨关节硬化症 (osteoarthrosis) 是一种两个孔的K通道.

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相关概念视频

Ion Channels01:19

Ion Channels

The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
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