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Updated: May 7, 2026

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人类中性粒细胞弹性酶:细胞内与细胞外抑制的表征

Denise Birk1,2, Erika Siepmann1, Stefan Simon1

  • 1Institute of Laboratory Medicine, University Hospital, LMU Munich, 80336 Munich, Germany.

International journal of molecular sciences
|July 27, 2024
PubMed
概括

中性粒细胞弹性酶 (HNE) 抑制剂可以在细胞内或细胞外工作,具有不同的效果. 了解细胞内抑制是开发新HNE治疗的关键.

关键词:
弹性酶抑制剂 弹性酶抑制剂中性粒细胞弹性酶.中性粒细胞中性粒细胞.

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Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.