饮食矿物质和事件心血管结果从不吸烟者在丹麦案例队列研究
Victoria Fruh1, Tesleem Babalola2, Clara Sears3
1Department of Environmental Health, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA.
,和等必需矿物质的饮食摄入量与心血管疾病风险没有一致的关联. 然而,一些证据表明潜在的U形关系,表明这些矿物质与心脏健康结果之间的复杂相互作用.
科学领域:
- 营养科学 营养科学
- 心血管流行病学心血管流行病学
- 饮食矿物质 饮食矿物质
背景情况:
- 饮食显著影响心血管疾病 (CVD) 的风险.
- 证据将必需矿物质 (Mg), (Ca) 和 (K) 与心血管疾病风险联系在一起是不一致的.
- 需要进行前性研究来澄清这些关联.
研究的目的:
- 调查饮食中综合摄入必需矿物质 (Ca,Mg,K) 与发生心血管疾病的风险之间的关联.
- 为了检查综合饮食摄入 (CDI) 评分和心力衰竭 (HF),急性心肌梗塞 (AMI) 和中风之间的关系.
- 澄清饮食中关键矿物质在预防心血管疾病中的作用.
主要方法:
- 在丹麦饮食,癌症和健康队列中进行了一项案例-队列研究.
- 在2015年之前,已经确定了HF,AMI和中风病例.
- 使用食物频率问卷评估了饮食中的矿物质摄入量,并计算了综合饮食摄入量 (CDI) 评分.
主要成果:
- 对于CDI得分和心血管疾病之间的关联,大多数危险比率 (HRs) 是零.
- CDI的第三个四分位数与中风风险降低有关 (HR:0.63;95% CI:0.44,0.88).
- 在第三个CDI四分位数中观察到对HF和AMI风险较低的趋势,尽管在所有分析中都不具有统计学意义.
结论:
- 没有一致的证据支持更高的必需矿物质摄入量可以降低发生的HF,AMI和中风的风险.
- 结果表明,选择矿物质和心血管疾病结果之间存在潜在的U形关系,需要进一步调查.
- 饮食中的矿物质和心血管健康之间的复杂相互作用需要更多的研究.
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