自生成的下体负压练习:对于急性太空任务的低功率对策
Suhas Rao Velichala1, Ryan D Kassel1, Victoria Ly1
1Department of Orthopaedic Surgery, UC San Diego Medical Center, University of California San Diego, La Jolla, CA 92093, USA.
Life (Basel, Switzerland)
|July 27, 2024
概括
自生成的下体负压 (LBNP) 显示了通过减轻液体转移来预防太空飞行相关的神经眼综合征 (SANS) 的前景. 这种方法有效地减少了内静脉的大小,模仿了太空飞行适应.
科学领域:
- 太空飞行生理学空间飞行生理学
- 心血管研究的心血管研究.
- 神经眼科神经眼科
背景情况:
- 微重力会导致液体向前移动,这可能是导致太空飞行相关神经眼综合征 (SANS) 的原因.
- 缓解这些流体变化对于宇航员健康和任务成功至关重要.
- 下体负压 (LBNP) 被探索为一种潜在的对策.
研究的目的:
- 评估自生成LBNP (SELF LBNP) 的生理影响,作为对抗微重力诱导的流体移动的对策.
- 为了比较SELF LBNP与传统的LBNP和对照条件 (直立和仰卧) 的疗效.
主要方法:
- 11名参与者接受了床上休息,以模拟微重力.
- 监测了生理反应,包括心率,血压和内静脉横截面积 (CSA).
- 参与者使用动力LBNP,动态SELFLBNP和控制位置进行了测试.
主要成果:
- SELF LBNP显著增加心率和血压 (p < 0.01).
- 与卧卧姿相比,SELF LBNP显著减少了右侧内静脉CSA (p = 0.005).
- SELF LBNP和传统的LBNP都减少了IJV CSA,传统的LBNP显示出明显的双边减少.
结论:
- SELF LBNP是对SANS的有希望的,低资源的对策,因为它有效地减少了流体转移.
- 它的低质量,体积和功率要求使其适合太空飞行.
- 在模拟太空飞行条件下进行进一步的长期研究是有必要的.
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