Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Obesity01:24

Obesity

418
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
418
Inflammation01:38

Inflammation

53.3K
Overview
53.3K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

27
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
27
Inflammatory Response01:28

Inflammatory Response

1.9K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
1.9K
Hypodermis01:02

Hypodermis

4.3K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
4.3K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Artificial Intelligence Applications in Implant Positioning, Dislocation Risk Prediction, and Surgical Indications in Orthopaedic Surgery.

Bioengineering (Basel, Switzerland)·2026
Same author

Robotic-Assisted Total Knee Arthroplasty: Current Evidence on PROMs, Functional Outcomes, Neuromotor Recovery, and Complications-A Narrative Review.

Medicina (Kaunas, Lithuania)·2026
Same author

Cutaneous Thermography in Arthropathies: Quantitative Imaging, Machine Learning, and Clinical Translation.

Journal of imaging·2026
Same author

A Systematic Review of the Clinical Impact of GLP-1 Receptor Agonists in Hidradenitis Suppurativa.

American journal of clinical dermatology·2026
Same author

A System in Motion: The Evolution of Orthopaedic Care in Romania.

The Journal of bone and joint surgery. American volume·2026
Same author

Diagnostic and prognostic biomarkers in heart failure and myeloproliferative neoplasms: clinical applications and risk scores - a narrative review.

Cardio-oncology (London, England)·2026

相关实验视频

Updated: Jun 18, 2025

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
07:46

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

25.2K

肥胖和炎症之间的相互作用

Ilinca Savulescu-Fiedler1,2, Razvan Mihalcea2, Serban Dragosloveanu3,4

  • 1Department of Internal Medicine, The "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Life (Basel, Switzerland)
|July 27, 2024
PubMed
概括

肥胖导致慢性炎症,特别是通过脂肪组织巨细胞. 了解这些炎症途径是开发新的肥胖治疗方法和管理相关疾病的关键.

关键词:
脂肪细胞 (adipocytes) 是一种脂肪细胞.亚迪波基因 (Adipokine) 是一种可靠的药物.脂肪组织的脂肪组织.细胞因子 细胞因子这是一种炎症炎症炎症炎症.巨细胞是什么?巨细胞是什么?肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖减肥 减肥 减肥 减肥 减肥 减肥

更多相关视频

Isolation of Adipose Tissue Immune Cells
07:09

Isolation of Adipose Tissue Immune Cells

Published on: May 22, 2013

36.2K
Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry
07:32

Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry

Published on: March 6, 2018

17.5K

相关实验视频

Last Updated: Jun 18, 2025

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation
07:46

Isolation, Characterization, and Purification of Macrophages from Tissues Affected by Obesity-related Inflammation

Published on: April 3, 2017

25.2K
Isolation of Adipose Tissue Immune Cells
07:09

Isolation of Adipose Tissue Immune Cells

Published on: May 22, 2013

36.2K
Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry
07:32

Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry

Published on: March 6, 2018

17.5K

科学领域:

  • 免疫学 免疫学 免疫学
  • 代谢障碍 代谢障碍 代谢障碍
  • 细胞生物学 细胞生物学

背景情况:

  • 肥胖严重影响患者的生活质量,并增加瘤和免疫介导疾病的风险.
  • 脂肪组织内的慢性炎症,由巨细胞调节,是肥胖的发展和进展的核心.
  • 脂肪组织中的巨细胞调节亲和抗炎性细胞因子分泌,影响代谢健康.

研究的目的:

  • 阐明炎症和脂肪组织巨细胞在肥胖中的作用.
  • 为了确定潜在的治疗干预的肥胖相关炎症的信号通路.
  • 了解炎症如何在减肥后持续存在及其对巨细胞表型的影响.

主要方法:

  • 关于肥胖,炎症和脂肪组织生物学现有文献的综述.
  • 分析巨细胞在与肥胖相关的慢性炎症中的作用.
  • 研究参与脂肪组织炎症的信号通路.

主要成果:

  • 炎症是肥胖的一个关键因素,巨细胞在脂肪组织中发挥着中心作用.
  • 脂肪组织中的特定信号通路与肥胖相关的炎症有关.
  • 减肥后持续的炎症可能涉及巨细胞表型的适应性变化.

结论:

  • 了解肥胖和慢性炎症之间的相互作用对于管理伴随疾病至关重要.
  • 准脂肪组织炎症和巨细胞活动为肥胖提供了潜在的治疗策略.
  • 对持续性炎症和巨细胞表型变化的进一步研究可以为未来的肥胖治疗提供信息.