识别肥胖的子周长切断点:与老年人慢性代谢疾病的关联
Dominique A Díaz1, Lydia Lera2, Carlos Márquez3,4
1Faculty of Health Sciences, Autonomous University of Chile, Santiago 7500000, Chile.
Journal of personalized medicine
|July 27, 2024
概括
子周长 (NC) 是识别老年人肥胖的一个有价值的工具. 较高的NC测量与糖尿病和高血压等慢性疾病的风险增加有关.
科学领域:
- 老年学是一门学科.
- 心血管健康 心血管健康
- 代谢健康 代谢健康
背景情况:
- 心血管疾病是老年人死亡的主要原因.
- 子周长 (NC) 是一个与脂肪相关的简单人体测量标志物.
- 现有的研究表明,需要验证NC作为老年人群中的脂肪性标志物.
研究的目的:
- 建立和验证子周长 (NC) 截止点,以识别老年人肥胖和肥胖.
- 分析NC与老年人心血管和慢性代谢疾病之间的关联.
- 提供一个简单的查工具,用于老龄化人口的健康风险.
主要方法:
- 一项涉及358名智利圣地亚哥社区老年人 (平均年龄71.7岁) 的横截面研究.
- 评估身体组成和心血管风险因素.
- 利用接收器操作特征 (ROC) 曲线和后勤回归来评估NC与疾病的关联,并确定肥胖和腹部肥胖的切断点.
主要成果:
- 对腹部肥胖的最佳NC截止点被确定为男性为40.6厘米,女性为34.2厘米.
- 较高的NC值显示出肥胖和肥胖的强度预测准确性 (男性AUC:0.84,女性:0.86).
- 在较高的NC和糖尿病风险增加 (OR=1.95),高血压 (OR=2.42),心肌梗塞 (OR=4.36) 和并发症 (OR=2.01) 之间发现了显著的关联,并降低了肉类的风险 (OR=0.35).
结论:
- 子周长作为一种有效和可访问的工具,用于检测肥胖,腹部肥胖和老年人的一般肥胖.
- 子周长升高是老年人患慢性代谢和心血管疾病风险增加的重要指标.
- 在老年人群中,NC测量提供了早期风险评估和潜在干预的实用方法.
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