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新德里金属β-乳糖酶抑制剂:一个系统的范围审查

Lutfun Nahar1, Hideharu Hagiya2, Kazuyoshi Gotoh3

  • 1Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

Journal of clinical medicine
|July 27, 2024
PubMed
概括

新德里金属β-乳糖酶 (NDM) 抑制剂在对抗多药耐药细菌方面表现有前景. 然而,目前没有NDM抑制剂被批准用于临床使用,这凸显了进一步研究和合作的必要性.

关键词:
抗微生物耐药性 抗微生物耐药性耐卡巴胺的肠道细菌产生碳酶的肠杆菌.组合组合组合的组合组合.金属β-β-乳酸酶的使用.协同效应是一种协同效应.

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Enzyme Inhibition01:30

Enzyme Inhibition

Inhibitors are molecules that reduce enzyme activity by binding to the enzyme. In a normally functioning cell, enzymes are regulated by a variety of inhibitors. Drugs and other toxins can also inhibit enzymes. Some inhibitors bind to the enzyme’s active site, while others inhibit enzymatic activity by binding to other sites on the protein structure.