在高加索儿童中控制近视,用0.01%的形眼滴:为期1年的随访研究
Dovile Simonaviciute1, Arvydas Gelzinis1, Laura Kapitanovaite2
1Department of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, 44037 Kaunas, Lithuania.
Medicina (Kaunas, Lithuania)
|July 27, 2024
概括
低剂量氨酸眼滴 (0.01%) 在一年以上的儿童中没有显著改变近视的进展. 然而,治疗组在研究期间的初始较高近视进展率下降.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 药理学 药理学是指药理学的学科.
背景情况:
- 近视是一种全球性眼睛疾病,患病率越来越高.
- 形眼滴是治疗近视进展的唯一药物治疗方法.
- 0.01%的氨酸眼滴正在研究其在近视控制中的有效性.
研究的目的:
- 为了评估0.01%的阿特罗宾眼滴对儿童近视进展的影响.
- 为了评估折射误差 (球形相当) 和轴长度的变化.
- 为了监测与0.01%的氨酸治疗相关的不良事件.
主要方法:
- 一项涉及近视的6-12岁健康儿童的研究.
- 使用0.01%的阿特罗宾眼滴的组与对照组之间的比较.
- 通过球形等效和轴长度变化在一年内评估近视的进展.
- 评估参与者和家长报告的不良事件.
主要成果:
- 一年后,在阿特罗平和对照组之间,球体等价或轴长变化没有显著差异.
- 0.01%的阿特罗宾组表现出他们以前更高的近视进展率的减少.
- 轻度不良事件,如视力模糊和光恐惧症,在16.4%的阿特罗平组报告.
结论:
- 与安慰剂相比,0.01%的阿特罗宾眼药在一年内对近视进展 (SE和AL) 没有显著影响.
- 在治疗一年期间,在阿特罗平组中观察到近视进展率的显著下降.
- 建议对近视管理的长期影响,反弹现象和更高度的亚氨酸进行进一步的研究.
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