在现实环境中对两个镜像显微镜设备的设备内部可重复性和设备间比较:Tomey EM-4000和Nidek CEM-53030
Mateusz Kecik1,2, Martina Kropp1,2, Gabriele Thumann1,2
1Department of Ophthalmology, University of Geneva, 1205 Geneva, Switzerland.
Medicina (Kaunas, Lithuania)
|July 27, 2024
概括
这项研究比较了Tomey EM-4000和Nidek CEM-530光谱显微镜用于角膜测量. 这两种设备都显示出可靠的结果,但在角膜内皮细胞密度和厚度方面发现了它们之间的显著差异.
科学领域:
- 眼科医生 眼科 眼科
- 医疗器械 医疗器械
- 角膜成像 角膜成像
背景情况:
- 镜像显微镜对于评估角膜健康至关重要.
- 将商业设备进行比较可以确保临床准确性和可靠性.
- 设备内部和设备间的可变性会影响诊断一致性.
研究的目的:
- 为了比较Tomey EM-4000和Nidek CEM-530镜头显微镜.
- 在临床环境中评估设备内部和设备间的变异性.
- 评估中央角膜厚度 (CCT) 和角膜内皮细胞密度 (ECD) 测量的可靠性.
主要方法:
- 分析了56名患者的112只眼睛.
- 每只眼睛都经历了每个镜头显微镜的三次测量.
- 统计分析包括正常性测试和比较测试 (Wilcoxon,t测试,ANOVA,曼-惠特尼).
主要成果:
- 这两种设备都显示出高的设备内部可重复性,用于ECD和CCT.
- 托米EM-4000:ECD 2390 ± 49.57 细胞/mm2,CCT 546 ± 5.104 微米. 这是一个很大的问题.
- 尼德克 CEM-530:ECD 2417 ± 0.09 细胞/mm2,CCT 546.3 ± 4.937 微米. 这是一个很好的方法.
- 在ECD (p=0.0175) 和CCT (p=0.0125) 之间观察到具有统计意义的设备间差异.
结论:
- 托米EM-4000和尼德克CEM-530都提供可靠和可复制的光谱显微镜结果.
- 绝对CCT和ECD测量在两个设备之间有很大的差异.
- 尼德克CEM-530往往会产生较高的CCT和ECD测量.
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