阶段角度作为预测年龄较大的部骨折患者的死亡率
Francisco José Sánchez-Torralvo1,2,3, Verónica Pérez-Del-Río3,4, Luis Ignacio Navas Vela1
1Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Regional Universitario de Málaga, 29007 Malaga, Spain.
Nutrients
|July 27, 2024
概括
通过生物电阻分析 (BIA) 测量的低相角与老年关节骨折患者的死亡风险更高有关. 这种简单的BIA测量可以预测手术后的生存结果.
科学领域:
- 老年学是一门学科.
- 生物医学工程 生物医学工程
- 临床医学 临床医学
背景情况:
- 关节骨折是老年人患病和死亡的一个重要原因.
- 生物电阻分析 (BIA) 是一种评估身体成分的非侵入性方法.
- 来自BIA的相角 (PhA) 可能反映细胞完整性和营养状况.
研究的目的:
- 为了研究老年患者的阶段角度和死亡率之间的关联,具有脆弱性关节骨折.
- 为了确定相角是否可以作为预后工具来预测这一群体的死亡率.
主要方法:
- 一项前性研究包括262名65岁以上的患者,他们因关节骨折住院治疗.
- 在手术后24~48小时进行生物电阻分析 (BIA).
- 死亡率被追踪到12个月,接收器运行特征 (ROC) 曲线确定了最佳相角截止值.
主要成果:
- 一,三,六和十二个月的死亡率分别为3.8%,8%,14.9%和20.2%.
- 预测12个月死亡率的最佳相角截止值为女性4.05°,男性4.65°.
- 低相角 (n=94) 的患者在所有时间点都表现出明显更高的死亡风险,即使经过对混因素的调整.
结论:
- 阶段角是骨骨折后老年人死亡率的重要独立预测因素.
- 低相角与手术后12个月内死亡风险增加2.8至5.1倍有关.
- 阶段角度可以作为一个有价值的预后工具来评估关节骨折患者的生存结果.
更多相关视频
09:51The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
Published on: September 7, 2022
2.6K
04:05Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
1.8K
相关概念视频
01:29Bone Disorders
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:09Changes in the Appendicular Skeleton with Age
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
01:20Actuarial Approach
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...