临床缓解期炎症性肠病患者的饮食概况-一项初步研究
Raquel Susana Torrinhas1, Ilanna Marques Gomes da Rocha1, Danielle Cristina Fonseca1
1Laboratory of Nutrition and Metabolic Surgery (LIM-35), Department of Gastroenterology, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de São Paulo, São Paulo 13563-120, Brazil.
炎症性肠道疾病 (IBD) 缓解期的患者仍然表现出显著的饮食失衡,特别是纤维和微量营养素摄入量低. 这些发现凸显了营养干预的必要性,即使IBD症状得到控制.
科学领域:
- 胃肠病学 胃肠病学
- 营养科学 营养科学
- 临床研究 临床研究
背景情况:
- 不均衡的饮食与炎症性肠病 (IBD) 的发展和活动有关.
- 饮食操纵可能有助于预防IBD复发,但缓解期患者的数据很少.
研究的目的:
- 描述临床缓解期IBD患者的饮食模式和营养充足度.
- 为了比较IBD患者和健康对照者的饮食摄入量.
主要方法:
- 采集了饮食摄入数据,使用40名IBD患者 (20名克罗恩病患者,20名性结肠炎患者) 和45名健康对照者的三个24小时食物记录.
- 使用统计测试 (t-测试,曼-惠特尼U,奇平方,费舍尔精确) 进行比较.
- 使用饮食参考摄入量 (DRI) 框架和估计平均需求 (EAR) 评估营养不充分的患病率.
主要成果:
- 与健康对照组相比,IBD患者表现出显著的宏观营养素和微量营养素摄入失衡.
- 在IBD患者中,总纤维和13种特定微量营养素的不足率超过80%.
- 饮食不平衡甚至在IBD患者的临床缓解期间仍然存在.
结论:
- 不平衡的饮食摄入量是IBD患者的特征,包括临床缓解期患者.
- 这些发现强调了饮食干预对控制IBD的重要性,即使是在非活跃阶段.
- 对IBD患者的向营养策略进行进一步的研究是有必要的.
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