微观结肠炎和腹腔疾病:共享的不仅仅是一个诊断重叠
Ana María González-Castro1,2, Fernando Fernández-Bañares3,4, Yamile Zabana3,4
1Translational Mucosal Immunology Laboratory, Vall d'Hebron Institut de Recerca, 08035 Barcelona, Spain.
Nutrients
|July 27, 2024
概括
微观性结肠炎和腹腔疾病具有共同的流行病学联系,约有6%的患者患有这两种疾病,特别是那些有耐火症状的患者. 建议在患有另一种疾病的患者中对一种疾病进行查.
科学领域:
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 微观性结肠炎 (MC) 是一种新出现的慢性结肠炎症疾病.
- 乳病 (CD) 是一种慢性质诱导的小肠肠肠病.
研究的目的:
- 审查MC和CD之间的流行病学,临床和病理生理学关系.
- 分析最近关于这两种胃肠道疾病之间关联的研究.
主要方法:
- 对现有文献进行了叙事审查.
- 分析的重点是流行病学,临床和病理生理学数据.
主要成果:
- 在大约6%的病例中,MC和CD同时发生,特别是在耐火患者中.
- 这两种疾病都涉及多因素免疫反应,共同的遗传因素和自身免疫.
- 观察到常见的临床症状和危险因素,以及与其他胃肠道疾病的重叠.
结论:
- 医生应该考虑查耐火性CD患者的MC,反之亦然.
- 需要进一步的研究来阐明CD和MC之间的关联背后的复杂的共享致病遗传机制.
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