全谷物摄入量与肥胖症之间的关联由不同的人体测量指标和美国患者的剂量反应关系分析来定义. 成年人:一个基于人口的研究
Yongjun Wang1, Jing Feng1, Tingting Liu1
1Key Laboratory of Public Nutrition and Health of National Health Commission, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Nutrients
|July 27, 2024
概括
较高的全谷物摄入量与较低的肥胖风险有关. 这项研究发现,增加全谷物消费显著降低了美国成年人普遍和腹部肥胖的几率.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 关于全谷物摄入量与肥胖之间的关联,存在不一致的证据.
- 有限的研究已经探索了全谷物消费和肥胖风险之间的剂量反应关系.
研究的目的:
- 调查全谷物摄入量与肥胖之间的关联.
- 为了检查全谷物摄入量与美国成年人肥胖之间的剂量反应关系.
主要方法:
- 分析了2003-2018年国家健康和营养检查调查 (NHANES) 中27862名美国成年人的数据.
- 用24小时的饮食回忆来评估全谷物摄入量.
- 肥胖是由体重指数 (BMI) 和腰围 (WC) 定义的;采用了后勤回归和受限制的立方脊柱模型.
主要成果:
- 与最低五分位数相比,全谷物摄入量的最高五分位数与普遍肥胖 (OR 0.79; 95% CI 0.72-0.88) 和腹部肥胖 (OR 0.80; 95% CI 0.73-0.89) 的几率明显降低.
- 受到限制的立方脊柱回归显示,全谷物摄入量和一般和腹部肥胖的患病率之间存在显著的反向线性剂量反应关系.
- 在研究人群中,一般肥胖的患病率为38.3%,腹部肥胖率为58.3%.
结论:
- 增加全谷物消费与普遍和腹部肥胖的几率降低有关.
- 研究结果支持全谷物在预防和管理肥胖方面的作用.
- 公共卫生建议应强调增加全谷物摄入量.
相关概念视频
Obesity
418
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
418
Cause and Effect
10.9K
While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
10.9K
Dose-Response Relationship: Overview
3.1K
Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
3.1K
Genome-wide Association Studies-GWAS
13.3K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.3K
Dose-Response Relationship: Potency and Efficacy
4.3K
The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it...
4.3K
Regulation of Food Intake
208
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
208


