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Updated: Jun 18, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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有效合成,结构特征,抗菌评估,ADME-毒素分析,分子对接和分子动力学模拟新功能化异醇的分子动力学模拟

Aziz Arzine1, Hanine Hadni2,3, Khalid Boujdi4

  • 1Engineering Laboratory of Organometallic, Molecular Materials and Environment, Faculty of Sciences Dhar EL Mahraz, Sidi Mohamed Ben Abdellah University, P.O. Box 1796, Atlas, Fez 30000, Morocco.

Molecules (Basel, Switzerland)
|July 27, 2024
PubMed
概括

新的异醇衍生物对常见的细菌菌株具有强大的抗菌活性. 化合物4a显示出显著的疗效,计算研究预测了有利的类似药物的特性和治疗潜力.

关键词:
在ADME-Tox中使用了ADME-Tox.模拟MD的模拟方法它具有抗菌活性,具有抗菌活性.晶体结构 晶体结构停靠的对接方式伊索克萨-结合剂的结合物

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