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在美国退伍军人中患有人类免疫缺陷病毒的临床定义的淋巴细胞瘤Venereum,2016-2023年

Gina Oda¹, Joyce Chung¹, Cynthia Lucero-Obusan¹

¹Public Health National Program Office, Department of Veterans Affairs, Washington, DC 20420, USA.

|July 27, 2024

概括

在HIV阳性退伍军人中,lymphogranuloma venereum (LGV) 可能被低估和治疗不足. 超过20%的甲状腺炎感染病例符合LGV标准,但接受推治疗的不到一半.

科学领域:

传染性疾病传染性疾病
公共卫生公共卫生
临床医学临床医学

背景情况:

淋巴细胞瘤 (Lymphogranuloma venereum,简称LGV) 是一种性传染性感染,由特定的克拉米迪亚白虫血清病毒引起.
艾滋病毒阳性个体可能面临性传播疾病 (包括LGV) 的风险增加,并且可能会出现不典型的表现.
准确诊断和及时治疗LGV对于预防严重并发症和进一步传播至关重要.

研究的目的:

为了确定艾滋病毒阳性退伍军人中LGV的流行率,他们感染了克拉米迪亚甲状腺虫 (CT) 感染.
在这个人群中确定与LGV相关的风险因素.
评估研究队列中LGV标准治疗方案的充分性.

主要方法:

在2016年至2023年期间,对1381名HIV和CT阳性退伍军人的回顾性队列研究.
应用LGV临床病例标准来诊断可能和可能的LGV病例.
对人口,临床和治疗变量进行分析,以确定风险因素和治疗模式.

主要成果:

20.6% (284/1381) 的艾滋病毒阳性退伍军人CT满足了LGV的临床标准.
主要的LGV风险因素包括出生时的男性性别,与男性发生性关系的男性以及与其他性传播感染的共同感染.
只有43.7% (124/284) 的LGV病例接受了标准推的治疗方案,可能的病例比可能的病例更有可能得到适当的治疗.

结论:

在美国,艾滋病毒感染的退伍军人中,LGV的诊断和治疗可能不足.
针对性查和更好地遵守治疗指南对于这种高风险人群是必要的.
需要进一步的研究来通过实验室检测确认LGV诊断,并优化管理策略.

关键词:

艾滋病病毒艾滋病病毒艾滋病病毒退伍军人退伍军人退伍军人克拉米迪亚感染感染.流行病学流行病学淋巴细胞瘤阴道瘤

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