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Updated: Jun 18, 2025

Evaluating Regional Pulmonary Deposition using Patient-Specific 3D Printed Lung Models
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向个性化萨尔布塔摩尔疗法:验证虚拟患者衍生的人口药理动力学模型与现实世界的数据

Lara Marques1,2,3, Nuno Vale1,2,3

  • 1PerMed Research Group, Center for Health Technology and Services Research (CINTESIS), Rua Doutor Plácido da Costa, 4200-450 Porto, Portugal.

Pharmaceutics
|July 27, 2024
PubMed
概括

这项研究开发了一个人群药理动力学 (popPK) 模型,用于治疗喘的药物萨尔布塔摩尔. 该模型确定了患者年龄,性别,种族和体重等因素如何影响萨尔布塔摩尔.

关键词:
在 PBPK 建模中使用 PBPK 模型.个体间的变异性.药物动力学 药物动力学popPK 建模 popPK 的建模盐胺醇的使用方法虚拟数据患者虚拟数据患者

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