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探索植物衍生纳米颗粒的生物医学前沿:合成和生物反应
Selvaraj Barathi1, Srinivasan Ramalingam2, Gopinath Krishnasamy3
1School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Pharmaceutics
|July 27, 2024
概括
来自植物的金属纳米粒子为治疗癌症和阿尔茨海默氏症等疾病提供了一种可持续且具有成本效益的方法. 这些使用植物提取物合成的纳米粒子在先进的生物医学应用和药物输送系统中显示出巨大的潜力.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术纳米技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 纳米粒子的生理化学合成是常见的,但有局限性.
- 来自植物的金属纳米颗粒提供了环保和成本有效的替代品.
- 植物二次代谢物是纳米粒子合成的关键前体.
研究的目的:
- 探索植物衍生金属纳米颗粒 (NP) 在疾病管理中的影响.
- 突出NP在下一代癌症,糖尿病,阿尔茨海默氏症和载体传播疾病治疗中的好处.
- 审查纳米配制技术和植物化合物在纳米粒子合成中的作用.
主要方法:
- 关于银纳米粒子 (AgNPs),金纳米粒子 (GtNPs) 和纳米粒子 (PtNPs) 的植物媒介合成的文献综述.
- 分析各种植物化合物的生物医学功能.
- 研究纳米粒子在药物输送,诊断和治疗中的应用.
主要成果:
- 植物提取物可以有效地合成AgNP,GtNP和PtNP.
- 植物化合物具有抗菌,抗氧化,抗癌和抗炎性质.
- 来自植物的NP在药物输送,诊断和治疗应用方面表现有前途.
结论:
- 来自植物的金属纳米粒子是新治疗策略的有希望的途径.
- 它们的生物相容性和药用特性使它们适合于先进的生物医学应用.
- 对NP毒性和向性治疗的进一步研究有必要进行临床转化.
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