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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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基于生理学的综合性药理动力学模型用于预测维尔达格利普丁的药理动力学:对脏功能障碍剂量的洞察

Mahnoor Pasha1, Ammara Zamir1, Muhammad Fawad Rasool1

  • 1Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60800, Pakistan.

Pharmaceuticals (Basel, Switzerland)
|July 27, 2024
PubMed
概括

基于生理学的药物动力学建模准确地预测了健康个体和慢性脏病患者的维达格利普丁药物水平. 这种验证的PBPK模型有助于优化功能障碍患者的药物剂量.

关键词:
慢性脏疾病 慢性脏疾病基于生理学的药物动力学模型.2 型糖尿病 2 型糖尿病维尔达格利普丁 (Vildagliptin) 是一种药物.

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