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Updated: Jun 18, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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TRIM5α:病毒识别和天生的免疫力的蛋白质建筑师

Stephanie J Spada1,2,3, Michael E Grigg2, Fadila Bouamr2

  • 1Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.

Viruses
|July 27, 2024
PubMed
概括

像TRIM5α这样的抗病毒限制因子进化以对抗病毒. 它的B30.2/PRYSPRY域识别病毒囊体,但TRIM5α也针对不同的病毒,表明更广泛的识别能力.

关键词:
这就是TRIM5α.具有天生的免疫力.整形花病毒的病毒.脊髓炎病毒 脊髓炎病毒它们是逆转录病毒.结构的结构结构的结构.

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