在患有先天性寨卡综合征的儿童中,睡眠与语言发展之间的关联
Nathani C da Silva1, Celia M Giacheti1, Maria C H do Couto1
1Department of Speech, Language and Hearing Sciences, São Paulo State University (UNESP), Marília 17525-900, Brazil.
Viruses
|July 27, 2024
概括
患有先天性寨卡病毒综合征 (CZS) 的儿童经常经历睡眠障碍和语言延迟. 睡眠问题可能会调解寨卡病毒脑部变化与受影响儿童语言发育障碍之间的联系.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿科神经学 儿科神经学
- 传染病对儿童发育的影响.
背景情况:
- 先天性寨卡病毒综合征 (CZS) 显著影响神经发育,特别是语言技能.
- 了解CZS中睡眠和语言发展之间的相互作用对于早期干预至关重要.
研究的目的:
- 为了研究患有CZS的儿童的睡眠模式和语言发育.
- 探索CZS中睡眠发育与神经发育的潜在同步.
主要方法:
- 对135名患有CZS的儿童 (0-48个月) 的横截面研究,使用BISQ用于睡眠和ELMS用于语言.
- 长度跟踪16名儿童 (最初为0-12个月),持续4年.
- 使用贝利尺度 (第三版) 评估运动,认知和社交能力.
主要成果:
- 观察到睡眠障碍和语言缺陷的高患病率.
- 在婴儿 (0-12个月) 中,晚上睡觉和夜间醒来与表达性语言较差相关.
- 较年长的儿童 (13-36个月) 显示了特定睡眠障碍 (夜间唤醒,睡眠开始延迟,睡眠时间缩短) 与受听和表达能力受损之间的关联.
结论:
- 寨卡病毒引起的大脑变化导致睡眠障碍和语言延迟.
- 睡眠障碍可能会成为中枢中心系统和语言发育延迟之间的关系的调解因素.
- 语言技能和睡眠参数之间观察到的相关性支持这种调解作用.
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