参与B细胞生长和HIV-1基因蛋白p17变体的克隆性活动的分子机制

Pasqualina D'Ursi1, Alessandro Rondina2, Alberto Zani2

  • 1Institute of Technologies in Biomedicine, National Research Council, 20090 Segrate, Italy.

Viruses
|July 27, 2024
PubMed
概括

人类免疫缺陷病毒 (HIV-1) 基因蛋白p17变体 (vp17s) 通过改变蛋白质结构来触发B细胞生长. 错误折叠暴露了一个功能性表位,促进B细胞克隆性和HIV-1患者的潜在淋巴发育.

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