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鸟类奥尔多病毒:对它们的分布,传播模式和基因型聚类进行系统审查

Saba Rafique¹, Farooq Rashid^2,3,4, You Wei^2,3,4

¹SB Diagnostic Laboratory, Sadiq Poultry Pvt. Ltd., Rawalpindi 46000, Pakistan.

|July 27, 2024

概括

禽类再病毒 (ARV) 对家禽构成全球威胁,造成经济损失. 本综述详细介绍了ARV流行,临床症状,基因型群和疫苗接种策略的挑战,以有效控制疾病.

科学领域:

兽医病毒学兽医病毒学
禽类的健康禽类的健康
传染性疾病传染性疾病

背景情况:

禽类甲状病毒 (ARV) 对家禽产业构成重大全球挑战,导致大量经济损失.
抗病毒药物对热量,酶,pH值变化和消毒剂具有耐药性,使商业家禽养殖场的根除工作复杂化.

研究的目的:

审查ARVs的全球流行,相关的临床表现和基因型特征.
分析ARV基因型集群与组织热带性或病毒分布之间的关系.
评估当前的疫苗接种策略,并确定改善ARV控制的需求.

主要方法:

全球ARV流行和临床症状的文献综述.
对ARV基因型集群 (I-VI) 和它们的地理分布进行分析.
检查ARV组织热带性,病毒分布和疫苗疗效.

主要成果:

常见的临床症状包括紧突炎/关节炎,吸收不良,发育迟缓和呼吸系统疾病.
在全球范围内,ARV基因型集群的流行率各不相同,非洲缺乏GC VI,而亚洲和美洲拥有所有GC.
在所有基因型集群中,紧突炎/关节炎是占主导地位的临床症状.

结论:

目前针对四种主要ARV菌株的疫苗可能无法提供足够的保护,防止各种现场隔离物.
抗逆转录病毒变种的出现需要进一步研究抗原和致病性质,以开发有效的疫苗.
结合改善疫苗接种,生物安全和农场管理的综合战略对于预防ARV感染至关重要.

关键词:

这就是ARV ARV.鸟类的复原病毒.基因型聚类的基因型聚类.这种病毒是Orthoreovirus.这就是Reovirus的原因.

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