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新型泛冠状病毒3CL蛋白酶抑制剂MK-7845:生物和药理分析

Nadine Alvarez1, Gregory C Adam2, John A Howe2

  • 1Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way, Nutley, NJ 07110, USA.

Viruses
|July 27, 2024
PubMed
概括

一种新的药物MK-7845显示出针对SARS-CoV-2和MERS-CoV的广泛活性. 这种新型3CLPro抑制剂显著降低了小鼠的病毒载荷,提供了潜在的泛冠状病毒治疗方法.

关键词:
3CLPro 3CLPro是3CLPro的产品之一.这就是MERS-CoV.这就是SARS-CoV-2病毒.抗病毒药物 抗病毒药物冠状病毒冠状病毒的新冠病毒.蛋白酶抑制剂是一种蛋白酶抑制剂.

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