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Updated: Jun 18, 2025

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一种基于突变M基因的活体减弱H1N1流感疫苗

Yinglei Yi1, Hongbo Zhang2, Youcai An2

  • 1Shanghai Institute of Biological Products, Shanghai 200052, China.

Vaccines
|July 27, 2024
PubMed
概括

这项研究通过突变PR8病毒的M基因开发了一种新的活体减弱型流感疫苗 (LAIV) 候选者. 由此产生的突变PR8 (mPR8) 疫苗表现出减少复制,并提供针对不同流感菌株的交叉保护.

关键词:
M 基因 基因 M 基因交叉保护 交叉保护流感病毒是流感的病毒.活体减弱疫苗的使用

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