在健康技术评估和健康经济学中捕捉疫苗的价值 - - 通过包括关键概念来扩大评估的实际考虑
Eliana Biundo1, Mariia Dronova2, Annie Chicoye3
1GSK, Building W23, 20 Avenue Fleming, 1300 Wavre, Belgium.
Vaccines
|July 27, 2024
概括
这项研究扩大了疫苗接种 (VoV) 框架的价值,包括在成本效益分析 (CEA) 中加强卫生系统,公平和宏观经济收益. 纳入这些更广泛的好处为决策者提供了更准确的VoV评估.
科学领域:
- 卫生经济学 卫生经济学
- 公共卫生政策 公共卫生政策
- 疫苗研究 疫苗研究
背景情况:
- 疫苗接种 (VoV) 框架的价值对于医疗技术评估 (HTA) 和成本效益分析 (CEA) 至关重要.
- 之前的框架确定了HTA/CEA的关键疫苗接种益处,但更广泛的影响需要进一步整合.
- 决策者需要全面的方法来评估疫苗接种计划的全部价值.
研究的目的:
- 提供方法和示例,将卫生系统加强 (HSS),公平性和宏观经济收益纳入VoV评估.
- 为了证明这些更广泛的好处如何影响疫苗接种HTA/CEA中的增量成本效益比率 (ICER).
- 提高VoV评估的准确性和完整性,以改善决策.
主要方法:
- 专家工作组的应用和有针对性的文献审查.
- 利用机遇成本方法来了解轮状病毒疫苗接种的HSS好处.
- 员工分配CEA,以获得脑膜炎球菌疫苗接种的健康公平利益,并为更广泛的经济影响进行宏观经济建模.
主要成果:
- 包括HSS福利在内,将轮状病毒疫苗接种的ICER降低了1.4-50.5%.
- 包括脑膜炎球菌疫苗接种的公平利益,使ICER减少了22-56%,在贫困群体中取得了显著的收益.
- 宏观经济模型可以通过评估对劳动力和更广泛的经济的影响来告知HTA过程.
结论:
- 可以评估和整合到当前的HTA/CEA中,包括HSS,公平性和宏观经济收益在内的更广泛的疫苗接种效益.
- 这些综合评估导致了更准确,更完整的VoV评估.
- 建议进一步完善方法和投入,特别是宏观经济收益.
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