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评估帕洛斯米亚患者:一项关于使用自我管理的帕洛斯米亚气味问卷评估方法的研究

M Tei¹, E Mori¹, N Yonezawa¹

¹Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, Japan.

|July 27, 2024

概括

帕洛斯米亚自行管理的气味问卷 (SAOQ-P) 在87%的患者中有效识别了帕洛斯米亚症状. 这种新工具有助于临床评估,突出了传统的嗅觉测试对parosmia诊断的局限性.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
神经科学是一个神经科学.
临床诊断临床诊断临床诊断

背景情况:

由于患者的异质性,帕洛斯米亚症状带来了重大的临床挑战.
量化帕洛斯米亚是很困难的,需要改进的诊断工具.
帕洛斯米亚自行管理的气味问卷 (SAOQ-P) 是作为现有问卷的修改而开发的.

研究的目的:

评估SAOQ-P在识别帕洛斯米亚症状方面的有效性.
评估SAOQ-P在临床评估过程中的潜在整合.
探索患有帕洛斯米亚和没有帕洛斯米亚的患者之间传统嗅觉测试结果的差异.

主要方法:

招募了在2022年5月至2022年11月期间出现在气味诊所的患者.
进行了SAOQ-P,包括对20种日常气味的附加问题.
传统的嗅觉测试包括T&T嗅觉测量和开放精华.

主要成果:

在279名患者中,81名患者患有帕洛斯米亚 (29%).
感染后和COVID-19后的嗅觉功能障碍病例显示出较高的帕洛斯米亚率.
在87%的受影响患者中,SAOQ-P检测出了帕洛斯米亚,咖啡,便和香水最常发生变化;传统测试显示没有显著差异.

结论:

在临床环境中,SAOQ-P是评估和量化帕洛斯米亚症状的有希望的工具.
调查问卷提供了有关帕洛斯米亚触发因素的见解.
传统的嗅觉测试的局限性突显出需要以患者为中心的诊断方法来诊断parosmia.

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